Pairnomix’s process of providing research services can be broken down into three steps.
1) Getting Started
After a patient receives genetic sequencing services from another company, the patient or family shares that information with us. We then evaluate all potential avenues for researching the identified pathogenic mutation, and outline a customized research plan with associated costs. Should the patient choose to move forward with the research plan, we receive a signed service order from the patient’s physician.
2) Gathering Data
We gather additional background information from the patient and perform the research. First, we create a laboratory model of the patient’s specific genetic mutation and perform experiments to understand the impact of the mutation on cellular function. Then, we test more than 1,300 approved drugs against the modeled mutation to understand their effects on the model.
3) Delivering Knowledge
Once we complete the research, we send a summary of our findings to the patient’s physician, and provide ongoing support and research updates to the patient and family.
Our research findings are provided to the physician in the form of informational reports:
- The cellular characterization report describes the normal cellular processes that are disrupted by the patient’s mutation.
- The drug screening report describes the activities of different drugs at the cellular level using laboratory models.
These documents provide details on the data we generated and the methods we used in our research. Pairnomix does not offer any recommendations based on our findings in these reports.
A member of our team is available to keep the patient, family, and physician updated and informed at every step of our process. This team member can provide additional support as needed and is also available to answer any questions relating to the findings presented in Pairnomix’s informational reports.
The costs and time requirements for our work are determined by the type of scientific research needed for a particular genetic mutation. If you are interested in our services, please don’t hesitate to connect with us. Our team will be happy to speak with you about the process, cost, and answer any questions you might have.