Pairnomix gives you the scientific insights you need to better understand your patient’s genetic sequencing result.
When Sequencing Alone Isn’t Enough
When you receive a genetic sequencing report that identifies a pathogenic mutation in your patient’s DNA, you finally know what’s causing your patient’s disease. But in many cases, you are still looking for more information.
Pairnomix’s research services are designed to fill this need.
The Pairnomix Difference
With these research efforts, we will create a laboratory model of your patient’s specific genetic mutation and perform experiments to understand the impact of that mutation on cellular function. We will then test more than 1,300 approved drugs against the modeled mutation for their abilities to reverse the mutation’s functional consequence. We will provide you informational reports that summarize these findings:
- The cellular characterization report describes the normal cellular processes that are disrupted by your patient’s mutation.
- The drug screening report describes the activities of different drugs at the cellular level using laboratory models.
These documents provide details on the data we generated and the methods we used in our research. Pairnomix does not offer any recommendations based on our findings in these reports.
When Should I Order Pairnomix’s Services?
Our services may be a good fit if you:
- Have ordered genetic sequencing for your patient, and sequencing has identified a pathogenic mutation
- Are seeking services to help you understand the functional consequences of your patient’s mutation and how drugs might affect these consequences in a laboratory model
While we focus on providing our services to physicians treating patients with epilepsy or seizure disorders, we also offer our services for other rare neurological diseases. Please click below to learn more about the process of working with Pairnomix, or contact us to discuss next steps.